Abstract: The manufacturing sector in Kenya plays a vital role in economic growth, employment creation, and industrial development. However, it faces persistent environmental and operational challenges due to inefficient logistics systems, resource-intensive production, and inadequate sustainability practices. This study evaluated how green logistic practices influence the supply chain sustainability of sugar companies in western Kenya. Specifically, it evaluated the effects of eco-friendly packaging on supply chain sustainability of sugar companies in western Kenya, examined the effect of green transportation on supply chain sustainability of sugar companies in western Kenya, evaluated the effect of green warehousing on supply chain sustainability of sugar companies in western Kenya, and to examine the effect of reverse logistics on supply chain sustainability of sugar companies in western Kenya. The study was anchored on natural resource-based theory. The study adopted a positivist philosophy and a descriptive and explanatory research design. The target population included factory managers, supply chain managers, operations supervisors, production managers, quality assurance managers, logistics personnel and warehouse managers. Data was collected through structured questionnaires and analyzed with help SPSS, employing descriptive statistics consisting of frequencies and percentages, correlation, and multiple regression analysis. Results were presented in tables. The study results found that green logistics practices have a significant and positive effect on supply chain sustainability among sugar manufacturing companies in Western Kenya. The regression results indicated that eco-friendly packaging (β = 0.657, p = 0.001), green transportation (β = 0.598, p = 0.000), green warehousing (β = 0.682, p = 0.000), and reverse logistics (β = 0.471, p = 0.007) all positively and significantly influence supply chain sustainability. Among these, green warehousing emerged as the strongest predictor. The model explained 62.3% of the variation in supply chain sustainability (R² = 0.623), indicating a strong explanatory power. Overall, the findings demonstrate that the adoption of integrated green logistics practices substantially enhances environmental and operational sustainability performance. The study recommends that sugar manufacturing firms should adopt an integrated green logistics strategy by strengthening eco-friendly packaging, enhancing green transportation systems, investing in energy-efficient warehousing, and improving reverse logistics practices. Firms should prioritize sustainable packaging materials, optimize transport operations, adopt renewable energy and automation in warehouses, and establish efficient product return and recycling systems. Additionally, policymakers should support these initiatives through environmental regulations, incentives, and infrastructure development to promote sustainable supply chain practices.